GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2243480 | 1 | rs34970380 | chr7:65431493 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 5.32 | 6.97E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs34974928 | chr7:65364006 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 4.78 | 6.3E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs35046236 | chr7:65408613 | CCT6P1 | chr7:65216092-65228661:+ | 0.62 | 5.13 | 1.51E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs35058610 | chr7:65390925 | CCT6P1 | chr7:65216092-65228661:+ | 0.68 | 4.97 | 3.0E-6 | Diabetic kidney disease |
| THYM | cis | rs4237643 | 1 | rs35060985 | chr11:43693110 | HSD17B12 | chr11:43702143-43878160:+ | -0.63 | -7.38 | 6.01E-11 | Forced vital capacity |
| THYM | cis | rs12780845 | 1 | rs35062783 | chr10:17202869 | CUBN | chr10:16865966-17171816:- | 0.31 | 4.8 | 5.85E-6 | Homocysteine levels |
| THYM | cis | rs6540731 | 1 | rs35209719 | chr1:212401677 | NEK2 | chr1:211836115-211848967:- | -0.16 | -4.42 | 2.59E-5 | Intelligence (childhood) |
| THYM | cis | rs2243480 | 1 | rs35283677 | chr7:65359233 | CCT6P1 | chr7:65216092-65228661:+ | 0.68 | 5.01 | 2.55E-6 | Diabetic kidney disease |
| THYM | cis | rs7246967 | 1 | rs35332070 | chr19:23034266 | ZNF492 | chr19:22817126-22850472:+ | -0.5 | -5.66 | 1.61E-7 | Bronchopulmonary dysplasia |
| THYM | cis | rs4924935 | 1 | rs35341640 | chr17:18818228 | FAM18B | chr17:18684582-18710026:+ | 0.26 | 4.53 | 1.73E-5 | Pancreatic cancer |
| THYM | cis | rs1577917 | 1 | rs35385043 | chr6:86648546 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -7.62 | 1.9E-11 | Response to antipsychotic treatment |
| THYM | cis | rs2243480 | 1 | rs35391607 | chr7:65360829 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 4.78 | 6.3E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs35396113 | chr7:65495461 | CCT6P1 | chr7:65216092-65228661:+ | 0.67 | 5.68 | 1.48E-7 | Diabetic kidney disease |
| THYM | cis | rs1577917 | 1 | rs35419329 | chr6:86702291 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs2243480 | 1 | rs35421653 | chr7:65363429 | CCT6P1 | chr7:65216092-65228661:+ | 0.68 | 5.01 | 2.55E-6 | Diabetic kidney disease |